Description:

Structure of organic compounds, properties of covalent bond, reactions on covalent bonds. Nomenclature of organic compounds (main chain, group, locants, prefixes and suffixes) . Spatial structures of organic compounds, double bond isomers, chirality, enantiomers and diastereomeric compounds. Configuration and conformation, relationships. Lewis structures, formal charges, acidity, hard and soft acids and bases. Resonance, aromaticity, classification of substituents, reactivity of polycyclic arenes. Intermediates: carbocations, carbanions, carbenes, radicals - electronic structure. Basic overview on alkanes and cycloalkanes, alkenes, arenes, halogenderivatives, organometallic compounds, alcohols and ethers, organic compounds of sulfur, nitrogen, phosphorus, silicon, other elements and carbonyl compounds chemistry.

Contents:

1. Introduction to organic chemistry, structural theories, main groups of organic compounds, nomenclature basics.
2. Chemical bonds in organic compounds, electronic effects, resonances, isomerism, conformations, configuration, chirality.
3. Alkanes and cycloaclanes ? nomenclature, structure, preparation, reactivity.
4. Alkenes, cycloalkenes, polyenes, alkynes ? nomenclature, structure, preparation, reactivity.
5. Arenes, theory of aromaticity, nomenclature, structure, preparation, reactivity.
6. Halogen derivatives ? nomenclature, structure, preparation, reactivity. Organometallic compounds.
7. Alcohols and Ethers, structure, preparation, reactivity.
8. Sulphides, other compounds of Sulphur, compounds of Phosphorus, Silicon and other elements ? nomenclature, structure, preparation, reactivity, their use.
9. Nitro- compounds and amines ? nomenclature, structure, preparation, reactivity and their use.
10. Amines ? reactivity, reactions of amines as bases and nucleophiles, diazo compounds and their reactions.
11. Carbonyl compounds, structure of carbonyl, reactivity centres, basic reactions of carbonyls.
12. Aldehydes and ketones ? nomenclature, structure, preparation, reactivity, adition of carbanions, condensation reactions.

Seminar contents:

1. Nomenclature of organic compounds
2. Structure of organic compounds, structural representations, structural models, isomerism
3. Basics of reactions mechanisms
4. Basics of organic synthesis
5. Reactions of alkenes, alkynes
6. Reactions and preparation of halogen derivatives
7. Reactions and preparation of alcohols and sulfides
8. Reactions and preparation of organometallic compounds
9. Reactions and preparation of amino-, nitro- a diazo- compounds
10. Condensation reactions and preparation of carbonyl compounds

Recommended literature:

Compulsory literature:
Smrček S., Kozempel J.: Electronic presentation of organic chemistry course, available on FNSPE website.

Other recommended literature:
McMurry J.: Organic chemistry, Brooks/Cole Cengage Learning, ISBN 9780534389994.
Lewis D.E. Organic Chemistry ? a Modern Perspective, Times Mirror Education Group, Inc. Dubunque 1996, ISBN 0697350916.

Keywords:

organic chemistry, structure of organic compounds, reaction mechanisms

Abbreviations used:

Semester:

• W ... winter semester (usually October - February)
• S ... spring semester (usually March - June)
• W,S ... both semesters

Mode of completion of the course:

• A ... Assessment (no grade is given to this course but credits are awarded. You will receive only P (Passed) of F (Failed) and number of credits)
• GA ... Graded Assessment (a grade is awarded for this course)
• EX ... Examination (a grade is awarded for this course)
• A, EX ... Examination (the award of Assessment is a precondition for taking the Examination in the given subject, a grade is awarded for this course)

Weekly load (hours per week):

• P ... lecture
• C ... seminar
• L ... laboratory
• R ... proseminar
• S ... seminar